Antibiotic | Dose (mg) | Interval |
---|---|---|
Trimethoprim-sulfamethoxazoled,e | 160/800 | q12h |
Norfloxacinf | 400 | q12h |
Ciprofloxacinf | 500 | q12h |
Levofloxacinf | 500 | q24h |
Cefixime | 400 | q24h |
Nitrofurantoin | 100 | q6h |
Amoxicillin plus clavulanate | 500 | q12h |
aDose modification is necessary in renal failure
bRegimens of 10-14 days are preferred for SOT recipients
c Previous microbiological results of the patients should be considered. Susceptibility of the pathogen to selected antibiotic must be confirmed with in vitro susceptibility testing of the urine sample
dNot appropriate as empirical treatment for SOT under prophylaxis with this antibiotic
eEmpirical use limited to those geographical areas where frequency of resistance is less than 20%
fFluorquinolones should be avoided in pregnancy, nursing mothers and adolescents younger than 17 years-old